Description
MOTS-c (Mitochondrial-derived Open Reading Frame of the 12S rRNA-c) is a relatively new peptide that is encoded within the mitochondrial genome. It is known for its role in regulating metabolic function, particularly in relation to insulin sensitivity and glucose metabolism. MOTS-c has been shown to mimic the effects of exercise, promoting metabolic homeostasis and protecting against age-related and diet-induced insulin resistance. It is being researched for its potential to combat obesity, diabetes, and other metabolic disorders.
Benefits:
- Improved Insulin Sensitivity: MOTS-c enhances insulin sensitivity, helping the body to utilize glucose more effectively, as demonstrated in research by Lee et al. (2015).
- Enhanced Physical Performance: Studies by Reynolds et al. (2021) have shown that MOTS-c can improve physical capacity and endurance, similar to the effects of exercise.
- Metabolic Regulation: It plays a key role in regulating metabolism, including fatty acid oxidation and glucose utilization.
- Anti-Aging: By improving mitochondrial function and metabolic health, MOTS-c has potential anti-aging effects.
Recommended Dosage: A common research dosage is 5-10 mg, administered 2-3 times per week. A 5mg vial is suitable for a single administration.
Recommended Stacks:
- Longevity & Anti-Aging Stack: MOTS-C works synergistically with NAD+ and Epithalon to support mitochondrial health and longevity.
- Performance & Body Composition Stack: For enhanced fat loss and performance, MOTS-C can be combined with Ipamorelin and Tesofensine.